Luteinizing hormone releasing hormone (LHRH) is a peptide hormone that stimulates the secretion gonadotropin hormones from the anterior pituitary. It is similar in structure to an agonist drug called Triptorelin, with the exception of a single amino acid substitution at the sixth position. The L-glycine is replaced by D-tryptophan. This substitution makes Triptorelin less susceptible to enzymatic cleavage, increasing its biological effectiveness.
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