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Action Potential

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Action potentials are depolarizations that start at the initial segment of an axon and are propagated toward the synaptic terminals. They are called “all-or-none” events because either an action potential is triggered or it is not; there is no in-between state. Prior to an action potential, the neuron is at rest, with a membrane potential of –70 mV. Now, if a stimulus depolarizes the cell to threshold, which is about –60 to –55 mV, voltage-regulated sodium channels in the membrane open. The sodium ions that rush across the cell membrane change the trans-membrane potential rapidly from threshold toward zero mV.

Duration: 00:53

Published: 11/25/2015

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