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Angiotensin II raises blood pressure in two ways. First, angiotensin II binds to receptors on the surface of smooth muscle cells within blood vessels; the resultant vasoconstriction increases peripheral vascular resistance. Second, angiotensin II stimulates the release of antidiuretic hormone (ADH) and aldosterone, which increase the tubular reabsorption of sodium and free water, increasing the total circulating blood volume. Together vasoconstriction and an increase in circulating volume raise blood pressure.
Duration: 01:01
Published: 8/9/2019
Blausen Medical
Scientific and Medical Animations
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